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pediatric

Flexible dosing* for parents to administer as needed 

Astepro® provides flexibility for parents to dose as needed.* It does not need to be used every day, or for several days to achieve maximum efficacy, unlike INS sprays that recommend daily dosing and can take between several days to 2 weeks to reach maximum efficacy levels.1-3,† 

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pediatric

Faster because it works differently

Astepro starts to work faster on the first day, compared with steroid allergy sprays, which require a longer, multi-step process to reach maximum efficacy levels.1-3,†

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pediatric

Steroid-free option for parents who want to avoid steroid use for their children4  

Astepro has no warning regarding pediatric growth suppression in its Drug Facts Label.4

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PROVEN EFFICACY IN PEDIATRIC POPULATION

In a 4-week trial of children 6 to <12:
Astepro significantly improved 12-hour combined AM + PM reflective TNSS 

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Results of a randomized, placebo-controlled, double-blind, parallel-group 4-week study of pediatric patients 6 to <12 years of age with moderate-to-severe symptomatic PAR (n=161 for patients receiving azelastine HCl 0.15% solution, and n=162 for patients receiving placebo). Primary endpoint was change from baseline in 12-hour combined AM + PM reflective TNSS.5 

 

 

RELIEF FOR CHILDREN WHILE INSIDE AND PLAYING OUTSIDE: 

Astepro delivers relief of indoor and outdoor allergy symptoms (nasal congestion, runny  nose, itchy nose, and sneezing) without steroids or an additional decongestant4 

 

 

 

 

THE SAME IMPROVED TASTE PROFILE AS PRESCRIPTION ASTEPRO®4,6

  • Includes the artificial taste-masking agent sucralose and sorbitol4 
  • In clinical trials, 94% of patients‡ receiving Astepro® reported no bitter taste6,7 

 

 

Pediatric dosing instructions4 

CHILDREN 6 YEARS TO 11 YEARS

  • An adult should supervise use
  • 1 spray in each nostril every 12 hours
  • Do not use more than 2 sprays in nostril in a 24 hour period.
    Do not use for children under 6 years

INS, intranasal steroid; PAR, perennial allergic rhinitis; TNSS, Total Nasal Symptom Score.
 *Up to twice daily.
 †INS onset based on various product information; time to maximum efficacy depends on the INS brand. 
‡12 years and older. 

REFERENCES
1. Flonase website. Frequently Asked Questions About Children’s Sensimist. Accessed February 18, 2022. https://www.flonase.com/products/childrens-sensimist/faqs/  2. Nasacort website. Children’s Nasacort Allergy 24HR. Accessed February 18, 2022. https://www.nasacort.com/for-childrens-allergies/ 3. Rhinocort website. Children’s Rhinocort Allergy Spray. Accessed February 18, 2022. https://www.rhinocort.com/allergy-nasal-spray/childrens-otc-spray 4. NDA 213872. 5. NDA 22-203. 6. Astepro®. Prescribing information. Meda Pharmaceuticals Inc; 2018. 7. van Bavel J, Howland WC, Amar NJ, Wheeler W, Sacks H. Efficacy and safety of azelastine 0.15% nasal spray administered once daily in subjects with seasonal allergic rhinitis. Allergy Asthma Proc. 2009;30(5):512-518. doi:10.2500/aap.2009.30.3284 

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